J Korean Radiol Soc.  1997 Nov;37(5):861-866.

Portal Vein Embolization with a New Embolic Material: Preliminary Study in Pigs

• Park SS
• Lee NS
• Kim TH
• Yoon HK
• Sung KB
• Song HY

Abstract

PURPOSE
To evaluate the usefulness of new liquid embolic materials for portal vein embolization (PVE).
MATERIALS AND METHODS
The liquid embolic material, Embol, was obtained by hydrolytic reaction of polyvinyl acetate (PVAc). Several Embols with a different hydrolysis ratio and polymer concentration were prepared and named, an example was Embol-78-12. These were percutaneously injected through a 5-Fr catheter into the left portal vein of six pigs, and radio-opacity under X-ray fluoroscopy and the possibility of reflux were evaluated.
RESULTS
The radio-opacity of Embol-78-8, Embol-73-10, and Embol-73-12 was too low to recognize reflux, but was excellent when Embol-78-12 or (Embol-78-12 + Lipiodol) was used; it was still difficult to prevent reflux, however. With the use of a balloon catheter, however, complete embolization became possible.
CONCLUSION
Embol-78-12 injection through a balloon catheter seems to be useful for clinical PVE.

Keyword

Animals; Portal vein, interventional procedure; Portal vein, therapeutic blockade

MeSH Terms

Animals
Catheters
Fluoroscopy
Hydrolysis
Polymers
Polyvinyls
Portal Vein*
Swine*
Polymers
Polyvinyls