J Korean Ophthalmol Soc.  2003 Jun;44(6):1328-1334.

Differentiating Patients with Glaucoma from Glaucoma Suspects by Retinal Nerve Fiber Layer Assessment Using Nerve Fiber Analyzer

• Hong HJ
• Cho HY
• Choi KR

Abstract

PURPOSE
To evaluate the difference of retinal nerve fiber layer measurements as obtained by Nerve Fiber Analyser according to visual field defects in subjects with large Cup-to-Disc ratio (C/D ratio>or=0.6) and to determine which predictable parameters are useful in glaucoma diagnosis. METHODS: Fifty one normal subjects, 17 patients with glaucoma, 18 glaucoma suspects based on optic disc appearance and visual field defect participated. Nerve fiber layer thickness assessments using scanning laser polarimeter (Nerve Fiber Analyzer II software version 2.1.; Laser Diagnostic Technologies, Inc., San Diego, California, U.S.A.) were measured in normal subjects, patients with glaucoma, and glaucoma suspects. Measured nerve fiber layer thickness parameters were compared each other. RESULTS: Superior to inferior ratio (S/I ratio) was only statistically significant parameter to differentiate glaucoma from glaucoma suspects having glaucomatous optic nerve head. CONCLUSIONS: Superior to inferior ratio (S/I ratio) is useful parameter to predict differentiating patients with glaucoma from glaucoma suspects.

Keyword

Glaucomatous optic nerve head; Glaucoma suspect; Nerve fiber layer thickness; Scanning laser polarimetry

MeSH Terms

California
Diagnosis
Glaucoma*
Humans
Nerve Fibers*
Optic Disk
Retinaldehyde*
Scanning Laser Polarimetry
Visual Fields
Retinaldehyde