J Korean Ophthalmol Soc.  2007 Jul;48(7):995-1000.

Two Cases of Presumed Graft Rejection after Deep Anterior Lamellar Keratoplasty

Affiliations
  • 1Department of Ophthalmology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. eschung@smc.samsung.co.kr

Abstract

PURPOSE: To report two cases of presumed immune-mediated stromal rejection developed after deep anterior lamellar keratoplasty (DALK).
METHODS
A 32-year-old woman and a 14-year-old man underwent DALK for keratectasia after LASIK surgery and keratoconus, respectively. Both patients developed stromal edema and peripheral corneal vascularization along the suture tract after the surgery. Under the impression of corneal stromal rejection, subconjunctival, oral, and topical steroid therapy were performed.
RESULTS
In both cases, vision improved, and complete reversal of stromal edema and regression of peripheral vascularization were attained.
CONCLUSIONS
Immune-mediated stromal rejection can occur after DALK surgery, which can be treated effectively by steroid therapy.

Keyword

Deep anterior lamellar keratoplasty; Immune-mediated stromal rejection; Steroid

MeSH Terms

Adolescent
Adult
Corneal Transplantation*
Edema
Female
Graft Rejection*
Humans
Keratoconus
Keratomileusis, Laser In Situ
Sutures
Transplants*
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