J Korean Neurol Assoc.
1990 Jun;8(1):180-184.
Two Cases of Familial Hypokalemic Periodic Paralysis
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- 1Department of Neurology, College of Medicine, Seoul National University, Korea.
Abstract
- Two patients of a family, suffenng from frequent periodic paralysis, were evaluated. Their family history reveals seven affected members in three generations, with autosomal dominance pattern. Their earliest symptoms were noticed between 10-13 years of age. The serum potassium level fell during the attack. EMG demonstrated progresslve reduction in numer of motor units and drop off in the response of muscle fibers to stimuli. These findings were consistent with familial hypokalemic periodic paralysis. The clinical features, electron microscoscopic findings, and pathogenesis were also described.
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