Korean J Med.  1998 Aug;55(2):259-264.

A Case of Chronic Inflammatory Demyelinating polyradiculoneuropathy with Intestinal Pseudoobstruction

Affiliations
  • 1Department of Neurology, Inje University, Sanggye Paik Hospital, Korea.
  • 2Department of Internal Medicine, Pathology, Hanil General Hospital,Seoul,Korea.

Abstract

Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) represents an important acquired condition characterized by progressive, symmetrical, proximal and distal weakness. CIDP is characterized by sensory loss and weakness, areflexia, elevated CSF protein and electrodiagnostic evidence of multifocal demyelination with or without superimposed axonal degeneration. Some reports are made that an antecedent illness in the weeks preceding the onset of symptoms such as upper respiratory syndrome or flu-like illness, gastrointestinal syndrome etc., but intestinal pseudoobstruction as the main clinical feature in CIDP is an uncommon finding. The clinical course is variable. The condition is responsive to immunosuppressive therapy, especially prednisone and plasma exchange. We report a case of intestinal pseudoobstruction secondary to CIDP diagnosed by clinical features, electrodiagnostic study and nerve biopsy pathology.

Keyword

Chronic inflammatory demyelinating polyneuropathy; Intestinal pseudoobstruction Electrodiagnostic study

MeSH Terms

Axons
Biopsy
Demyelinating Diseases
Intestinal Pseudo-Obstruction*
Pathology
Plasma Exchange
Polyradiculoneuropathy, Chronic Inflammatory Demyelinating*
Prednisone
Prednisone
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