J Korean Radiol Soc.  1997 Mar;36(3):499-502.

Measurement of Renal Cortical Thickness Using Spiral CT in Early Diabetic Nephropathy

Affiliations
  • 1Department of Diagnostic Radiology, College of Medicine, Dong-A University.

Abstract

PURPOSE
To compare the ratio of renal cortical thickness to renal parenchymal thickness in early diabetic nephropathy and in normal control group.
MATERIALS AND METHODS
We performed spiral CT in 17 patients suffering from diabetic nephropathy without renal failure or renal atrophy. The normal control group consisted of 19 persons who were normal on renal function test and did not show any abnormality of the kidney. Renal cortical and parenchymal thicknesses were measured at renal hilum level perpendicular to the renal surface by electronic caliper on contrast-enhanced transverse scan demonstrating the cortical nephrogram phase. Using student's test, the difference in renal parenchymal and cortical thickness between the two groups was tested for statistical significance.
RESULTS
There was no significant difference in renal parenchymal thickness between the two groups(P>0.05) ; the patient group had a thicker renal cortex than the normal control group however (P<0.05). The ratio of renal cortical thickness to parenchymal thickness in early diabetic nephropathy patients(Rt.:0.041+/-0.051, Lt.:0.382+/-0.053) was significantly higher than in the normal control group (Rt.:0.331+/-0.067, Lt.:0.323+/-0.064).
CONCLUSION
The kidney of early diabetic nephropathy patients had a thicker renal cortex than normal kidney.

Keyword

Kidney, CT; Kidney, diseases; Diabetes Mellitus, complications; Computed tomography (CT), helical

MeSH Terms

Atrophy
Diabetic Nephropathies*
Humans
Kidney
Renal Insufficiency
Tomography, Spiral Computed*
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