J Korean Diabetes Assoc.  2007 Mar;31(2):130-135. 10.4093/jkda.2007.31.2.130.

Waist Circumference May be More Important than Body Mass Index (BMI) in Determinants of Left Ventricular Mass in Korean Hypertensive Patients

• Lim YH
• Park BH
• Kim SZ
• Cho CG

• KMID: 2008081
• DOI: http://doi.org/10.4093/jkda.2007.31.2.130

Abstract

BACKGROUND: In many studies, obesity is highly correlated with adverse coronary risk profile. Increased left ventricular (LV) mass is an independent risk factor for cardiovascular mortality and morbidity. Hypertension is an well known factor related with LV mass. Obesity also is related with LV mass and commonly associated with hypertension. However, few data are available concerning the relations of LV mass to central obesity, especially in Korean hypertensive patients. So, this study was to evaluate the significance of waist circumference in determinants of LV mass in Korean hypertensive patients.
METHODS
A total of 74 hypertensive [40 women, 34 men; mean age, 62.5 years; mean body mass index (BMI), 25.0 kg/m2, 17 with type 2 diabetes] patients without prevalent cardiovascular disease were studied. Echocardiographic LV septal thickness, LV posterior wall thickness, LV dimension and LV mass were analysed.
RESULTS
LV mass, diastolic left ventricular internal dimension and epicardial fat thickness were larger in men than in female. LV mass was larger in obese patients defined by body mass index and also in central obese patients defined by waist circumference. LV mass was correlated with sex, body mass index, waist circumference, diastolic left ventricular internal dimension, left ventricular posterior wall thickness and interventricular septal thickness. After controlling for age, sex and body mass index, waist circumference was correlated with LV posterior wall thickness and LV mass.
CONCLUSION
Waist circumference may be more important than BMI in determinants of left ventricular mass in Korean hypertensive patients.

Keyword

Hypertension; LV mass; Obesity; Waist circumference

MeSH Terms

Body Mass Index*
Cardiovascular Diseases
Echocardiography
Female
Humans
Hypertension
Male
Mortality
Obesity
Obesity, Abdominal
Risk Factors
Waist Circumference*

Figure

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  Fig. 1 Left ventricular mass in normal (BMI < 23 kg/m2) and obese (BMI > 25 kg/m2) hypertensive patients.

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  Fig. 2 Comparison of left ventricular mass between non-central obese and central obese hypertensive patients.

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