J Korean Soc Radiol.  2010 May;62(5):497-500. 10.3348/jksr.2010.62.5.497.

Aggressive Desmoid Tumor Mimicking Breast Cancer

• Park JY
• Ko MS
• Kim HH
• Shin HJ
• Hwang JE
• Gong GY
• Ahn SH

• KMID: 2002960
• DOI: http://doi.org/10.3348/jksr.2010.62.5.497

Abstract

A desmoid tumor of the breast is a rare benign disease that mimics a breast malignancy. An accurate diagnosis of a desmoid tumor is difficult because it frequently infiltrates the surrounding tissue and often recurs after excision. We report a case of a 72-year-old female presenting with an aggressive desmoid tumor that mimicked breast carcinoma.

MeSH Terms

Aged
Breast
Breast Neoplasms
Female
Fibromatosis, Aggressive
Humans
Ultrasonography, Mammary

Figure

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  Fig. 1 Medio-lateral oblique and cranio-caudal mammographic views of the left breast shows a large, irregular shaped, hyperdense mass with an ill-defined margin and located in the upper outer quadrant, which appeared to infiltrate the pectoral muscle (arrowheads) and retract the overlying skin.

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  Fig. 2 Ultrasound images show an irregularly shaped hypoechoic mass with speculation.

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  Fig. 3 Gross cross-sectional view of the pathology specimen. The pinkish-white fibrotic mass shows an infiltrating extension into the breast parenchyma (arrows) and pectoral muscle (arrowheads).

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  Fig. 4 Microscopic examination shows spindle cells with collagen. The spindle cells have small, pale, oval or spindly nuclei without nuclear atypia or pleomorphism, and the mitotic figures are inconspicuous (hematoxylin-eosin, ×400).

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  Fig. 5 Microscopic examination shows spindle cells invading and engulfing the ducts (arrows) and stromal adipose cells (arrowheads) (A, hematoxylin-eosin, ×100) and muscles (arrow) (B, hematoxylin-eosin, ×200).

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