J Korean Soc Radiol.  2013 Jun;68(6):483-487. 10.3348/jksr.2013.68.6.483.

Renal Metastasis from Primary Cervical Cancer: A Case Report

• Jeon SW
• Kim SH
• Kwon SY

• KMID: 2002900
• DOI: http://doi.org/10.3348/jksr.2013.68.6.483

Abstract

Metastasis of malignant tumors to the kidney is clinically rare and often discovered by autopsy. Primary lymphoma and lung cancer are known that can metastasize to the kidney. Other malignant tumor metastasis to the kidney is very unusual. Primary cervical cancer metastasis to adjacent pelvic organs and lymph nodes are well known followed by abdominal solid organs such as the liver and adrenal glands. However, reported primary cervical cancer metastasis to the kidney is extremely rare and mostly appeared as bilateral multiple renal masses. We report here on a rare case of unilateral single renal metastasis from primary cervical cancer after concurrent chemoradiotherapy.

MeSH Terms

Adrenal Glands
Autopsy
Chemoradiotherapy
Kidney
Liver
Lung Neoplasms
Lymph Nodes
Lymphoma
Neoplasm Metastasis
Positron-Emission Tomography
Uterine Cervical Neoplasms

Figure

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  Fig. 1 Non enhanced axial CT (A) scan shows enlarged kidney with a ill defined soft tissue like density mass (arrowheads) in the right kidney. Excreatory phase scan (B) shows 75 × 59 × 47 mm sized mass with subtle enhancing portion in the peripheral area. Also, conserved adjacent renal cortex and reniform (arrowheads) that near the mass was seen. An enlarged necrotic lymph node (black arrow) in retrocaval area near the site of right renal vein insertion to inferior vena cava also was seen. Excreatory phase coronal CT (C) scan shows focal ill-defined low density portion of renal cortex suspecting infiltration of adjacent renal mass (arrowhead). Nephrographic phase coronal CT (D) scan shows encroachment of adjacent renal artery, vein branches and upper ureter (arrow).

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  Fig. 2 Follow-up PET-CT scan reveal intense FDG uptake mass (arrowhead) in the right kidney and hypermetabolic enlarged LN (arrow) in the retrocaval chain. There shows multiple nodularity and irregular thickening of the left pleura with marked FDG uptake with large amount of left pleural effusion. Note.-FDG = fluorodeoxyglucose, LN = lymph-node, PET = positron emission tomography

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  Fig. 3 Longitudinal gray scale sonogram of the right kidney (A) show hypo to intermediate echogenic mass (arrows) in renal pelvis without definite combined hydronephrosis. A linear hyperechoic lesion is biopsy needle (arrowhead). Longitudinal color Doppler image (B) shows the hypovascular nature of the lesion (arrows).

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  Fig. 4 Histologic and immunohistochemical features of squamous cell carcinoma of the cervix and the kidney. Histologic finding of tumor from the cervix shows poorly differentiated squamous cell carcinoma (A, H&E, × 400). Histologic findings of tumor from the kidney reveal poorly differentiated squamous cell carcinoma (B, H&E, × 400). Immunohistochemical stainings of kidney reveal negativity for AMARCAR (C, × 400).

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