Korean J Obstet Gynecol.  2012 Apr;55(4):265-268. 10.5468/KJOG.2012.55.4.265.

A case of spindle cell carcinoma of the uterine cervix

• Choi SA
• Lee MR
• Kim MJ
• Jeon HJ
• Kim YS
• Bae DH
• Kim CJ

• KMID: 1992624
• DOI: http://doi.org/10.5468/KJOG.2012.55.4.265

Abstract

Spindle cell carcinoma is a rare variant of squamous cell carcinoma characterized histologically by a biphasic pattern with both squamous and spindle cell component. There is controversy in the histogenesis, biologic behavior, optimal treatment and prognostic factor for tumor. Treatment must be similar for squamous cell carcinoma. With a review of literature, we report a case of a 52-year-old female with spindle cell carcinoma in the uterine cervix, which has been managed by total hysterectomy.

Keyword

Spindle cell carcinoma; Uterine cervix; Hysterectomy

MeSH Terms

Carcinoma, Squamous Cell
Cellular Structures
Cervix Uteri
Female
Humans
Hysterectomy
Middle Aged

Figure

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  Fig. 1 Punch biopsy reveals carcinoma composed of spindle cells (H&E, ×200).

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  Fig. 2 (A) Cone biopsy of the cervix shows squamous cell carcinoma, focal fascicles of proliferating spindle cell, which considerable mitotic activity, and focal moderate degree of nuclear atypia (H&E, ×400). (B) Immunohistochemical finding shows positive reaction for smooth muscle actin (smooth muscle antigen, ×400).

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