Korean J Obstet Gynecol.  2012 Jul;55(7):507-512. 10.5468/KJOG.2012.55.7.507.

A Case of Recurrent Ovarian Granulosa Cell Tumor Associated with Sarcomatoid Change

Affiliations
  • 1Department of Obstetrics, Yeungnam University School of Medicine, Daegu, Korea. djlee@med.yu.ac.kr
  • 2Department of Pathology, Yeungnam University School of Medicine, Daegu, Korea.

Abstract

Granulosa cell tumors of the ovary are malignancies that originate from the sex-cord stromal cells of the ovary and represent 2% to 5% of all ovarian cancers. Slow growth with a tendency for late recurrence characterizes a natural history of this tumor. So this tumor needs a prolonged follow-up. As a result of recent literature in Korea, the findings are 3 cases of juvenile granulosa cell tumor and 1 case of adult granulosa cell tumor. Previous case of adult granulosa cell tumor was presented recurrence with hepatic metastasis after 9 months of first diagnosis and operation. We describe here a 52-year-old women with recurrent granulosa cell tumor after total abdominal hysterectomy with right salpingo-oophorectomy and left ovarian wedge resection because of right ovarian granulosa cell tumor 12 years ago. Our case presented late recurrence character of granulosa cell tumor. We report 1 case of recurrent adult type granulosa cell tumor associated sarcomatoid change with a brief review of literatures.

Keyword

Granulosa cell tumor; Recurrent; Sarcomatoid change
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