Korean J Urol.
1989 Apr;30(2):143-147.
Urothelial Tumors of the Upper Urinary Tract: Multiplicity and Prognostic Variables
- Affiliations
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- 1Department of Urology, Keimyung University, School of Medicine, Taegu, Korea.
Abstract
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Transitional cell carcinoma of the upper urinary tract is distinguished from other genitourinary malignancy by its tendency to be part of a generalized abnormality that affects the entire urothelium and causes multiple tumors. We analyzed retrospectively 30 patients who underwent nephroureterectomy for transitional cell carcinoma of the renal pelvis and ureter. High stage upper urinary tract transitional cell carcinoma and a history of synchronous bladder transitional cell carcinoma were adverse prognostic factors. We observed increased incidence of additional urothelial tumors in more than 50 per cent of patients, especially on the involved side, which mandated radical nephroureterectomy including a bladder cuff as the treatment of choice.