Korean J Nephrol.
1999 Jul;18(4):634-638.
A Case of Disseminated Nocardiosis in Kidney Transplant Recipient
- Affiliations
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- 1Department of Internal Medicine, College of Medicine, Yeungnam University, Taegu, Korea.
Abstract
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Nocardiosis is a rare infection seen most commonly in immunocompromized patients.
Most patients have pulmonary involvement, but some develop disseminated infection.
A 52-year-old man, treated with immunosuppressive drugs for 3 months after kidney
transplantation, developed pulmonary nocardiosis and disseminated infection involving brain,
skin, and both uvea. The diagnosis was made by open lung biopsy specimens showing
characteristic weak acid fastness with modified Ziel-Neelsen stainig and histologic
examination. Immunosuppressive therapy was continued and combination of surgical drainage
of brain abscess and chemotherapy with Minocycline were successful. With the increasing
number of allograft recipients and concomitant immunosuppression, the possibility of an
increase in Nocardia opportunistic infections exists.