Korean J Pediatr Hematol Oncol.
2000 Apr;7(1):141-145.
Three Cases of Trilateral Retinoblastoma
- Affiliations
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- 1Department of Pediatrics, Korea Cancer Center Hospital, Seoul, Korea.
Abstract
- Retinoblastoma is the most common ocular malignancy in childhood. The association of bilateral retinoblastoma with ectopic midline intracranial tumor, trilateral retinoblastoma syndrome, is rare, but the prognosis is very poor with even with various combination treatments of surgery, chemotherapy, and radiotherapy including neuraxis. The cause of treatment failure was tumor dissemination along the neuraxis in approximately 50% of the cases. We experienced three cases of trilateral retinoblastoma, and two of them are alive so far with multi-modal treatment.
