Korean J Pathol.
2014 Apr;48(2):146-150.
Multifocal Osteosarcoma of the Skull: Multiple Primary or Metastatic? A Case Report
- Affiliations
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- 1Department of Pathology, Kyung Hee Medical Center, Kyung Hee University College of Medicine, Seoul, Korea. ykpark@khmc.or.kr
- 2Department Neurosurgery, Kyung Hee Medical Center, Kyung Hee University College of Medicine, Seoul, Korea.
Abstract
- Osteosarcoma of the skull is a very rare condition. Moreover, it is extremely rare for osteosarcoma to present as multiple lesions confined to the skull. A 58-year-old woman was admitted with two masses in the parietal area of the skull, accompanied by mild headache and tenderness. Imaging revealed two masses with a heterogeneous consistency in the cranial bones. Excision craniectomy was performed and the pathology was consistent with osteoblastic osteosarcoma. Two nodules in the heart were found on routine follow-up imaging while the patient was undergoing chemotherapy. The nodules were biopsied and found to be metastatic osteosarcoma.
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