Korean J Pathol.
2014 Apr;48(2):126-132.
Characteristics of Cutaneous Lymphomas in Korea According to the New WHO-EORTC Classification: Report of a Nationwide Study
- Affiliations
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- 1Department of Pathology, Ajou University School of Medicine, Suwon, Korea.
- 2Department of Pathology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
- 3Department of Pathology, Inje University Seoul Paik Hospital, Seoul, Korea.
- 4Department of Pathology, Konkuk University School of Medicine, Seoul, Korea.
- 5Department of Pathology, Veterans Health Service Medical Center, Seoul, Korea.
- 6Department of Pathology, Korea University College of Medicine, Seoul, Korea.
- 7Department of Pathology, Inje University Sanggye Paik Hospital, Seoul, Korea.
- 8Department of Pathology, Hallym University Sacred Heart Hospital, Anyang, Korea.
- 9Department of Pathology, Hanyang University College of Medicine, Seoul, Korea.
- 10Department of Pathology, Asan Medical Center, Seoul, Korea.
- 11Department of Pathology, Korea University Guro Hospital, Seoul, Korea.
- 12Department of Pathology, Yonsei University College of Medicine, Seoul, Korea.
- 13Department of Pathology, Hanyang University Guri Hospital, Guri, Korea.
- 14Department of Pathology, Gyeongsang National University School of Medicine, Jinju, Korea.
- 15Department of Pathology, Kyung Hee University School of Medicine, Seoul, Korea.
- 16Department of Pathology, Dankook University College of Medicine, Cheonan, Korea.
- 17Department of Pathology, Eulji University Hospital, Daejeon, Korea.
- 18Department of Pathology, Eulji General Hospital, Seoul, Korea.
- 19Department of Pathology, Seoul National University, Seoul, Korea. cwkim@snu.ac.kr
- 20Department of Pathology, Ulsan University College of Medicine, Ulsan, Korea.
- 21Department of Pathology, Chonnam National University Medical School, Gwangju, Korea.
Abstract
- BACKGROUND
Previously, cutaneous lymphomas were classified according to either the European Organization for the Research and Treatment of Cancer (EORTC) or the World Health Organization (WHO) classification paradigms. The aim of this study was to determine the relative frequency of Korean cutaneous lymphoma according to the new WHO-EORTC classification system.
METHODS
A total of 517 patients were recruited during a recent 5 year-period (2006-2010) from 21 institutes and classified according to the WHO-EORTC criteria.
RESULTS
The patients included 298 males and 219 females, and the mean age at diagnosis was 49 years. The lesions preferentially affected the trunk area (40.2%). The most frequent subtypes in order of decreasing prevalence were mycosis fungoides (22.2%), peripheral T-cell lymphoma (17.2%), CD30+ T-cell lymphoproliferative disorder (13.7%), and extranodal natural killer/T (NK/T) cell lymphoma, nasal type (12.0%). Diffuse large B-cell lymphoma accounted for 11.2% of cases, half of which were secondary cutaneous involvement; other types of B-cell lymphoma accounted for less than 1% of cases.
CONCLUSIONS
In comparison with data from Western countries, this study revealed relatively lower rates of mycosis fungoides and B-cell lymphoma in Korean patients, as well as higher rates of subcutaneous panniculitis-like T-cell lymphoma and NK/T cell lymphoma.
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