Chonnam Med J.  1996 Jun;32(1):7-12.

Clinical utility of MRI in heterotopia and correlation with seizure

• Ko SW
• Kim YH
• Seo JJ
• Kang HK
• Jeong YY
• Chung HD

Abstract

PURPOSE: To evaluate types of gray matter heterotopias, and its correlation with the patterns of seizure.
MATERIALS AND METHODS
We evaluated retrospectively 13 patients (male:female=5:8) with gray matter heterotopias on brain MRI. Using 1.5T GE Signa Advantage Unit, spine echo T1-, proton-density and T2-weighted images in axial, coronal and sagittal planes were obtained.
RESULTS
Types of gray matter heterotopias were subependymal in seven patients, and subcortical in six. Associated anomalies were seen in three patients: other neuronal migration anomalies in two patients, Dandy-Walker malformation in one. Ten patients had seizure, but patterns of seizure were not correlated with types of heterotopia.
CONCLUSION
Gray matter heterotopias can be classified as subepedymal and subcortical types. On MRI, heterotopias showed same signal intesity with gray matter in all imaging sequences, and patterns of seizure (main clinical manifestation) were not correlated with types of gray matter heterotopia.

MeSH Terms

Brain
Dandy-Walker Syndrome
Humans
Magnetic Resonance Imaging*
Neurons
Retrospective Studies
Seizures*
Spine