Ann Coloproctol.  2013 Jun;29(3):130-134. 10.3393/ac.2013.29.3.130.

Mucosal Schwann-Cell Hamartoma Diagnosed by Using an Endoscopic Snare Polypectomy

Affiliations
  • 1Department of Internal Medicine, The Catholic University of Korea College of Medicine, Seoul, Korea. shjung74@catholic.ac.kr
  • 2Department of Pathology, The Catholic University of Korea College of Medicine, Seoul, Korea.

Abstract

Colorectal polyps of mesenchymal origin are a rare group of colorectal disorders. A "mucosal Schwann-cell hamartoma," which is one type of polypoid lesion that originates from the mesenchyme, is a newly-proposed disease entity to be distinguished from the neurofibromas found in type-1 neurofibromatosis. This lesion is composed of pure Schwann-cell proliferation in the lamina propria and shows diffuse immunoreactivity for the S-100 protein. We report a case of a polypoid lesion of the colon with the features of this recently-proposed disease entity.

Keyword

Schwann cells; Hamartoma; Neurofibroma; Neuroma; Colon polyps

MeSH Terms

Colon
Hamartoma
Mesoderm
Mucous Membrane
Neurofibroma
Neurofibromatoses
Neuroma
Polyps
S100 Proteins
Schwann Cells
SNARE Proteins
S100 Proteins
SNARE Proteins
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