Ewha Med J.  1983 Mar;6(1):23-27. 10.12771/emj.1983.6.1.23.

A Comparative Study on the Clinical Effects of Various Topical Corticosteroids by Psoriasis Plaque Test

Affiliations
  • 1Department of Dermatology, College of Medicihe, Ewha Womans University, Korea.

Abstract

The psoriasis plaque test, as a clinical and non-artificial model, provides information on the antiproliferative effect of topical corticosteroids, and it makes possible to ealuate various preparations simultaneously at a given time. In this assay we compared the antiproliferative effects of six topical corticosteroids with occlusive dressing technique in fourteen psoriatic patients. The results are summerized as follows : 1) The psoriasis plaque test was an adequate method for evaluating antiproliferative effects of various corticosteroid preparations. 2) In contrast to prednisolone and triamcinolone acetonide, the effects of desoxymethasone, halcinonide, fluocinide, triamcinolone benetonide were evident, and the best of all was desoxymethasone. 3) No side effect developed during test period.


MeSH Terms

Adrenal Cortex Hormones*
Desoximetasone
Halcinonide
Humans
Occlusive Dressings
Prednisolone
Psoriasis*
Triamcinolone
Triamcinolone Acetonide
Adrenal Cortex Hormones
Desoximetasone
Halcinonide
Prednisolone
Triamcinolone
Triamcinolone Acetonide
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