J Korean Neurol Assoc.
2011 Nov;29(4):339-342.
Anti-NMDA Receptor Encephalitis
- Affiliations
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- 1Department of Neurology, College of Medicine, Chungbuk National University, Cheongju, Korea. sunghlee@chungbuk.ac.kr
Abstract
- A severe, but reversible encephalitis associated with antibodies to the N-methyl-D-aspartate receptor (NMDAR) was identified recently in young women with ovarian teratoma. This condition has not been reported previously in Korea. A 31-year-old woman presented with fever and behavioral disturbances; she became comatose several days later, and dyskinesia and dysautonomia developed thereafter. Antibodies to the NMDAR were positive and abdominal computed tomography detected a large ovarian teratoma. The patient improved dramatically after the removal of the teratoma and administration of corticosteroid therapy.