J Korean Androl Soc.  1995 Dec;13(2):107-112.

Diagnostic Efficiency of CIS Test and DICC in Venogenic Impotence

Affiliations
  • 1Department of Urology, Korea University College of Medicine, Seoul, Korea.
  • 2Department of Urology, Dankook University College of Medicine, Cheonan, Korea.

Abstract

Combined intracavernous injection and stimulation(CIS) has been applied in clinical settings to screen for organic causes of erectile dysfunction. Although dynamic infusion cavernosometry and cavernosography(DICC) has been accepted as the most useful diagnostic modality for venogenic impotence, standardizing the testing and its interpretation has been controversial because of the relatively high false-positive rates. Our aims were to determine the reliability of the CIS test and each parameter of DICC in 42 impotent patients. The result of the CIS test were categorized as good, fair or poor, depending on the level of erection and its rigidity, duration and adequacy for sexual intercourse. In the patients with fair or poor responses, penile duplex doppler ultrasonography was performed to exclude an arteriogenic origin of their problem. Venogenic impotence was diagnosed by DICC when the patient met one or more of the following critera: equilibrium pressure <90mmHg, maintenance flow rate >40mL/min, or rate of fail >1.5mmHg/sec. Six patients(14%) were found to have psychogenic, 23(55%) venogenic and 13(31%) mixed arteriogenic and venogenic impotence. According to the outcome of the CIS test, 8 patients(19%) were placed in the fair-response group and the remaining 34 in the poor-response group. The results of this test and the components of DICC did not correlate(p>0.05). However, the correlation between the CIS test result and the measures of venogenic impotence showed a positive predictive value of 85.7%. The correlations between each component of the DICC and venogenic impotence were statiscally significant(p<0.02). Among the components of the DICC, the rate of fall demonstrated the highest sensitivity(100%) and specificity(80%). Our results suggest that the CIS test alone was inadequate for the diagnosis of venogenic impotence, whereas the DICC, especially the rate of fall, is excellent, whereas if the CIS test result is combined with the DICC, especially the rate of fall, it may be a useful and effective tool for the accurate diagnosis of venogenic impotence.


MeSH Terms

Coitus
Diagnosis
Erectile Dysfunction
Female
Genetic Complementation Test*
Humans
Impotence, Vasculogenic*
Male
Ultrasonography, Doppler, Duplex
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