J Korean Acad Rehabil Med.
1997 Feb;21(1):186-193.
A Histochemical Changes of Calf Muscle Fibers after Rat Hindlimb Suspension
- Affiliations
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- 1Department of Rehabilitation Medicine, Inha University College of Medicine, Korea.
- 2Department of Rehabilitation Medicine, Korea University College of Medicine, Korea.
Abstract
- purpose
of this study was to investigate alterations in histochemical properties in the gastrocnemius & soleus muscles of rats following hindlimb suspension for 1 week. A modification of the Morey and Musacchia models was used to determine atrophic responses of rat muscle. The weights of rat's whole body and of gastrocnemius and soleus muscles were affected by suspensions. A reduction of type I distribution was accompanied by an increase in type II fibers. The cross sectional area of all fiber types was reduced after suspension. These results suggest that type I fibers showed greater susceptibility than type II fibers and some amount of type I fibers might have been converted to type II fibers.
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