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J Korean Med Assoc.  2014 Nov;57(11):949-956. 10.5124/jkma.2014.57.11.949.

Percutaneous left ventricular assist device: a systematic review

Affiliations
  • 1Division for New Health Technology Assessment, National Evidence-based Healthcare Collaborating Agency, Seoul, Korea. ujin@neca.re.kr

Abstract

The percutaneous left ventricular assist device (pLVAD) was developed for short-term use in patients who require acute circulatory support. The TandemHeart system can be inserted percutaneously in the cardiac catheterization laboratory using standard insertion techniques. The objective of this review is to evaluate the safety and effectiveness of pLVAD only for the TandemHeart. The searches were conducted via electronic databases including Medline, Embase, and the Cochrane library, and 942 non-duplicate citations were retrieved. A total of 20 studies (two randomized controlled trials, one cohort study, and 17 case series) were included for this review. Two review authors independently applied the extracted data and assessed the study quality. On the basis of current data, we recommend that the pLVAD be used as a potential treatment for rescue by the mechanical management of cardiogenic shock. On the other hand, the prophylactic use of the pLVAD requires more evidence from larger more effectively designed studies.

Keyword

Heart-assist devices; Hemodynamics; Percutaneous coronary intervention; Shock, cardiogenic

MeSH Terms

Cardiac Catheterization
Cardiac Catheters
Cohort Studies
Hand
Heart-Assist Devices*
Hemodynamics
Humans
Percutaneous Coronary Intervention
Shock, Cardiogenic
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