J Korean Neurol Assoc.  1992 Sep;10(3):395-400.

A Case of Multiple Mononeuropathy Associated with Polyarteritis Nodosa

• Lee SH
• Rho SK
• Song CW
• Lee SI
• Park KH
• Kim SW

Abstract

Polyarteritis nodosa(PAN) has been depicted as a necrotizing arteritis of small and medium-sized muscular arteries, affecting multiple organ systems throughout the body. The etiology of PAN remains unknown, but the histopathologic resemblance to chronic serim sickness has suggested an immune complex pathogenesis. The peripheral nervous system(PNS) is more frequently affected (in about 20-50% of patients) than the central nervous system(in about 10-20% of patients). Although multiple mononeuritis multiplex is generally considered to be the typical PNS manifestation of PAN, distal symmetrical polyneuropathy may occur more frequently than previous recognized. We report a case of polyarteritis nodosa with mononeuritis multiplex and distal symmetrical polyneuropathy, which was diagnosed by electrophysiological study and biopsies of muscle and sural nerve.

MeSH Terms

Antigen-Antibody Complex
Arteries
Biopsy
Mononeuropathies*
Polyarteritis Nodosa*
Polyneuropathies
Sural Nerve
Antigen-Antibody Complex