J Korean Neurosurg Soc.  1995 Apr;24(4):430-434.

Stereotactic Removal of Spontaneous Intracerebral Hematoma Using Hematome and Urokinase

• Noh JS
• Pyen HS
• Hu C
• Hong SK
• Kim HJ
• Han YP

Abstract

We had tried to perform mechanical aspiration using Hematoma and fibrinolytic drainage with Urokinase for treatment of spontaneous intracerebral hematoma(SICH) in 24 patients. Mean initial volume of SICH was 53.65+/-26.34 ml, mean evacuated amount of SICH after Hematoma procedure was 46.25+/-23.64%, and mean evacuated amount of SICH after fibrinolytic drainage after Urokinase was 74.15+/-20.89%, compared with pre-operative status. We could aspirate more than 50% of hematoma if the Hematoma procedure had been performed within 18 hours after ictus(p=0.0306). The rebleeding rate after Hematoma procedure was 8.3%, and overall mortality rate was 12.5%. There results seem to indicate mechanical aspiration using Hematoma and fibrinolytic drainage with Urokinase might be one of the useful method for treatment of SICH.

Keyword

Spontaneous intracerebral hematoma(SICH); Hematoma; Urokinase

MeSH Terms

Drainage
Hematoma*
Humans
Mortality
Suction
Urokinase-Type Plasminogen Activator*
Urokinase-Type Plasminogen Activator