J Korean Radiol Soc.  1997 Jul;37(1):71-77.

Renal Angiomyolipoma: Superselective Arterial Embolization and Long Term Follow-up

Affiliations
  • 1Department of Diagnostic Radiology, Chonbuk National University Medical School.
  • 2Institute for Cardiovascular Research, Chonbuk National University Medical School.
  • 3Department of Pathology, Chonbuk National University Medical School.
  • 4Department of Urology, Chonbuk National University Medical School.
  • 5Department of Diagnostic Radiology, Wonkang University Medical School.
  • 6Department of Diagnostic Radiology, Daejeon Ul Ji Medical College.

Abstract

PURPOSE
To evaluate the effectiveness of superselective arterial embolization in symptomatic renal angiomyolipoma by assessing tumoral changes and clinical symptoms in long term follow up after embolization.
MATERIALS AND METHODS
For the treatment of their condition, nine patients with symptomatic renal angiomyolipoma underwent ten superselective arterial embolization procedures. In all patients, angiomyolipoma had been diagnosed by computed tomography (CT), and in two, had been confirmed by ultrasonography-guided aspiration biopsy. The embolic materials used were absolute alcohol in four sessions, absolute alcohol mixed with lipiodol in three, and Giantruco coils in three. In all patients, follow-up after embolization lasted for between 12 and 54 months, and involved the use of CT. We reviewed retrospectively patients' clinical symptoms, and changes in the size and internal components of tumors, as seen on preembolization and postembolization CT scans.
RESULTS
On postembolization angiography, devascularization of the tumor was seen in all patients; the initial symptoms disappeared and tumor size decreased during the follow up period. In nine patients, tumor size decreased after embolization by between 26 and 92%. During the long term (over 12 months) follow up of all patients, seven tumors with a considerable angiomyogenic component markedly decreased in size, but tumors in which the mature fatty component was substantial became only slightly smaller. Reembolization was performed in one patient.
CONCLUSION
Superselective arterial embolization is effective in the management of symptomatic renal AML; during long-term follow-up, tumors became smaller and clinical symptoms improved. Embolization is more effective in tumors in which the angiomyogenic components is large.

Keyword

Angioma, genitourinary system; Kidney neoplasms, therapy; Arteries, Therapeutic blockade

MeSH Terms

Angiography
Angiomyolipoma*
Biopsy, Needle
Ethanol
Ethiodized Oil
Follow-Up Studies*
Humans
Retrospective Studies
Tomography, X-Ray Computed
Ethanol
Ethiodized Oil
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