J Korean Soc Emerg Med.  2002 Mar;13(1):106-109.

Case Report of Tetanus Which is Treated by Human Tetanus Immunoglobulin 500 Unit

• Cho SH
• Cho NS
• Kim MR
• Ju S

Abstract

Tetanus is a neurologic disorder, characterized by increased muscle tone and spasms, that is caused by tetanospasmin, a powerful protein toxin elaborated by Clostridium tetani. In the modern society, tetanus is a rare disease, but it has a high mortality on attack and it 's diagnosis depends on the clinical symptoms. The treatment for tetanus is an injection of human tetanus immunoglobulin (HTIG) to neutralize the circulating tetanospasmin, to control breathing, and to provide systemic supportive care. Recently, the 500 unit of HTIG is recommended. We report one case of generalized tetanus that was treated with 500 units of HTIG. The patient was discharged without complications.

Keyword

Tetanus; Human tetanus immunoglobulin

MeSH Terms

Clostridium tetani
Diagnosis
Humans*
Immunoglobulins*
Mortality
Nervous System Diseases
Rare Diseases
Respiration
Spasm
Tetanus*
Immunoglobulins