J Korean Soc Radiol.  2014 May;70(5):355-358. 10.3348/jksr.2014.70.5.355.

The Combination of Neuroendocrine Tumor and Mucinous Neoplasm of the Appendix: A Case Report

• Suh HB
• Lee NK
• Kim S
• Park WY
• Kim JH

• KMID: 1941781
• DOI: http://doi.org/10.3348/jksr.2014.70.5.355

Abstract

Primary neoplasm of the appendix is an uncommon pathology, representing 0.5-1% of all appendix specimens. Especially, simultaneous occurrence of two tumors of the appendix was rarely documented. We report a case of the concomitant neuroendocrine tumor and the mucinous neoplasm of the appendix on abdominal computed tomography, in a 62-year-old female who came for a check-up.

MeSH Terms

Appendix*
Female
Humans
Middle Aged
Mucins*
Mucocele
Neuroendocrine Tumors*
Pathology
Mucins

Figure

• 

  Fig. 1 A 62-year-old woman who presented with a neuroendocrine tumor and mucinous cystadenoma in the appendix. A. Axial contrast-enhanced CT shows a 1.1 cm sized well-defined enhancing mass (arrow) in the orifice of the appendix. B. Axial contrast-enhanced CT (caudal than A) shows a cystic mass (arrow) with peripheral calcification contiguous with base of cecum. C. Coronal-reformatted contrast-enhanced CT shows the rupture of the cystic mass (arrow) and periappendiceal fluid collection. Scalloping of the liver margin (arrowheads) is noted. D. Photograph of the cut gross specimens reveals cystic dilation of the appendix (arrows) and a subserosal mass (arrowheads) at the orifice of the appendix. E. Photomicrograph (original magnification, × 20 hematoxylin-eosin stain) of cystic dilation in the appendix shows replaced neoplastic mucinous epithelium with single layers, sometimes with papillary tufting. Nuclei are small and regular with low grade dysplasia. F. Photomicrograph (original magnification, × 20 hematoxylin-eosin stain) of the mass in the orifice of the appendix shows neoplastic neuroendocrine cells arranged in rounded solid nests. Tumor cells show moderate pleomorphism with occasionally seen hyperchromatic and large nuclei.

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