Korean J Anesthesiol.  2006 Apr;50(4):469-473. 10.4097/kjae.2006.50.4.469.

Central Pontine Myelinolysis after Liver Transplantation: A case report

• Jeong HK
• Gwak MS
• Kim GS

• KMID: 1936718
• DOI: http://doi.org/10.4097/kjae.2006.50.4.469

Abstract

Hyponatremia is common in end stage liver disease and central pontine myelinolysis (CPM) can occur after the rapid correction of hyponatremia. The blood sodium concentration can increase rapidly during the perioperative period of liver transplantation due to the administration of sodium-containing fluids and blood products. We experienced 5 cases of CPM after liver transplantation. Major changes in the blood sodium concentrations occurred during surgery in the first 3 cases while these changes occurred after surgery in the last 2 cases. We reviewed the blood sodium concentrations of these 5 patients and speculated on the correlation of CPM with a rapid increase in the blood sodium concentration.

Keyword

central pontine myelinolysis; hyponatremia; liver transplantation

MeSH Terms

End Stage Liver Disease
Humans
Hyponatremia
Liver Transplantation*
Liver*
Myelinolysis, Central Pontine*
Perioperative Period
Sodium
Sodium