Korean J Dermatol.
2007 Apr;45(4):387-390.
A Case of Pigmented Neurofibroma Associated with Giant Cafe-au-lait Patches
- Affiliations
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- 1Department of Dermatology, College of Medicine, Dong-A University, Busan, Korea. leecw@dau.ac.kr
Abstract
- Pigmented neurofibroma is a rare cutaneous tumor accounting for less than 1% of all neurofibroma. It is characterized histologically by the coexistence of scattered melanin-laden cells and benign spindle cells with neural differentiation. The origin of these tumors are unknown, and they show a storifom pattern. In our case, the patient had giant cafe au lait patches on the left trunk which had been present since birth, freckles on both axilla, and two dark-red colored plaques which had appeared 2 years ago. Histologic examination revealed pigmented neurofibromas showing the melanin-laden, pigmented cells within the upper dermis and plexiform neurofibromas in the subcutaneous tissue. We describe a case of pigmented neurofbroma in a 13-year-old male patient.
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