Korean J Spine.  2015 Jun;12(2):95-98. 10.14245/kjs.2015.12.2.95.

Treatment of Polyostotic Fibrous Dysplasia of the Thoracic Spine with Intravenous Pamidronate: Result from 9 Months Follow Up

• Lee J
• Shin H
• Kwon YJ

• KMID: 1927567
• DOI: http://doi.org/10.14245/kjs.2015.12.2.95

Abstract

Fibrous dysplasia of the spine is very rarely observed. We reported a case of a 57-year-old woman, who presented with neck and bilateral shoulder pain with histologically confirmed fibrous dysplasia, involving the first and second thoracic vertebrae. Clinical and radiological findings were not specific for fibrous dysplasia. The histological biopsy was required for a confirmed diagnosis. Endocrine and metabolic evaluations are required to rule out diseases such as hyperthyroidism, Cushing syndrome and osteomalacia. Fibrous dyplasia can be managed by appropriate medical and surgical treatments based on the patient's neurological status and symptoms. Our patient was given intravenous pamidronate 60mg/day for 3 days. After 9 months, her initial symptoms were improved, but computed tomography scan of the thoracic spine showed no change of the lesions.

Keyword

Fibrous dysplasia of bone; Thoracic spine; Pamidronate

MeSH Terms

Biopsy
Cushing Syndrome
Diagnosis
Female
Fibrous Dysplasia of Bone
Fibrous Dysplasia, Polyostotic*
Follow-Up Studies*
Humans
Hyperthyroidism
Middle Aged
Neck
Osteomalacia
Shoulder Pain
Spine*
Thoracic Vertebrae