Korean J Obstet Gynecol.  2003 Dec;46(12):2486-2491.

A Case of Partial Hydatidiform Mole with a Coexistent Live Fetus

• Kim YS
• Lee HH
• Kim HM
• Cho IS
• Kim TH
• Shim YK
• Nam KH
• Lee KH
• Park SJ
• Koh ES
• Lee IS

Abstract

Hydatidiform moles are generally separated into two classifications. Complete hydatidiform moles are characterized by cystic swelling of all villi, often pronounced diffuse trophoblastic hyperplasia, lack of fetal parts, all 46 chromosomes of paternal origin (androgenesis). Partial hydatidiform moles appear to be focal trophoblastic hyperplasia, a fetus or indications of previous fetal existence, 69 chromosomes. Hydatidiform mole with coexistent fetus is a very rare phenomenon, with an estimated incidence of 0.005 to 0.01 percent of all pregnancies and associated with a risk of persistent gestational trophoblastic tumor. Recently, hydatidiform moles with a fetus have become more common due to use of assisted reproductive technology. Most patients with hydatidiform mole and coexisting normal fetus must cautioned about the potential for risks of malignant change and severe medical complications, such as preeclampsia, hyperthyroidism and antepartum hemorrhage, that may necessitate prompt pregnancy termination. We experienced a case of partial hydatidiform mole with coexistent live fetus, which was diagnosed by ultrasonography at 15 gestational weeks. A brief reviews of related literature was done.

Keyword

Hydatidiform mole; Partial hydatidiform mole; Coexisting fetus; Trophoblastic disease

MeSH Terms

Classification
Female
Fetus*
Hemorrhage
Humans
Hydatidiform Mole*
Hyperplasia
Hyperthyroidism
Incidence
Pre-Eclampsia
Pregnancy
Reproductive Techniques, Assisted
Trophoblastic Neoplasms
Trophoblasts
Ultrasonography