J Korean Cleft Palate-Craniofac Assoc.  2010 Oct;11(2):99-102.

Primary Parotid Non-Hodgkin's Lymphoma: A Case Report

Affiliations
  • 1Department of Plastic and Reconstructive Surgery, Kangnam Sacred Heart Hospital, Hallym University Medical Center, Seoul, Korea. sismdps@chol.com
  • 2Department of Pathology, Kangnam Sacred Heart Hospital, Hallym University Medical Center, Seoul, Korea.

Abstract

PURPOSE
Primary malignant lymphomas of the salivary glands are uncommon, representing only 1.7% to 3.1% of all salivary neoplasms and 0.6% to 5% of all tumors and tumor-like lesions of the parotid gland. Lymphomas of the parotid glands are usually manifestations of a systemic disease process but primary lymphomas of the parotid glands are rare. Most of these lesions are classified as extranodal non-Hodgkin's lymphoma. We report the clinicopathological features of primary malignant lymphoma of the parotid gland based on an analysis of our cases.
METHODS
The subject was a 48-year-old male patient with a malignant lymphoma originating in the parotid gland, which had been slowly increasing in size over previous 6 months. The diagnosis was established by MRI and a superficial lobectomy. After diagnosis, the patient was referred to an oncologist for staging and medical treatment.
RESULTS
The stage was IIIA. The patient was treated with chemotherapy following surgery with rituximab and CHOP (Cyclophosphamide, Adriamycin, Vincristine, Prednisolone). The tumor was controlled successfully by chemotherapy. The patient was followed up for 1 year with no relapse.
CONCLUSION
A case of primary non-Hodgkin's lymphoma of the parotid gland was treated with a superficial parotidectomy and chemotherapy. The disease was well controlled after a 1 year follow-up.

Keyword

Non Hodgkin's lymphoma; Parotid gland

MeSH Terms

Antibodies, Monoclonal, Murine-Derived
Doxorubicin
Follow-Up Studies
Humans
Lymphoma
Lymphoma, Non-Hodgkin
Male
Middle Aged
Parotid Gland
Recurrence
Salivary Glands
Vincristine
Antibodies, Monoclonal, Murine-Derived
Doxorubicin
Vincristine
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