Arch Aesthetic Plast Surg.  2012 Oct;18(3):133-137.

Application of Newly Developed Acellular Dermal Matrix Allograft (CG DermTM) in Breast Reconstruction with the Implant: The Prospective Study

• Kim YS
• Jeong BR
• Hong JW
• Roh TS
• Rah DK

Abstract

Several freeze-dried human acellular dermal matrix have been introduced and they helped to facilitate implant based breast reconstruction by providing support to the breast lower pole, firm fixation of inframammary fold, and simple operation procedure. We evaluated clinical outcomes of recently produced human acellular dermal matrix, CG Derm(TM), prospectively. CG Derm(TM) was used in six patients and eight breasts for implant breast reconstruction. Complete blood cell count test, rountine chemisty(including ESR) test, and CRP test were performed before and after the surgery. Postoperative complication was evaluated including infection, seroma, implant malpostion, rippling deformity, and capsular contracture. Randomly selected two patients underwent breast MRI after reconstruction. Finally we examine patients' satisfaction survey and plastic surgeons' evaluation. Satisfactory breast lower pole fullness, symmetric inframammary folds and breast shapes were achieved in most patients. Overall, patients had sufficient aesthetic satisfaction and surgeon's evaluation was also good. There was no major complication except four cases of seroma which healed with conservative management. Implant breast reconstruction using CG Derm(TM) was safe and obtain good aesthetic results. But further and larger scale study should be performed to reveal out the relatively high risk of seroma.

Keyword

Breast reconstruction; Breast implant; Allograft; Skin substitutes

MeSH Terms

Acellular Dermis
Blood Cell Count
Breast
Breast Implants
Congenital Abnormalities
Contracture
Female
Humans
Mammaplasty
Postoperative Complications
Prospective Studies
Seroma
Skin, Artificial
Transplantation, Homologous