A trying to evaluate acute renal tubular damage after ESWL

Kim, Jong Soung; Rim, Joung Sik

Abstract

Determination of urinary marker proteins was carried out trying to evaluate renal tubular damage as a part of renal injury caused by ESWL via EDAP LT-01+lithotiptor. All of twenty patients undergoing ESWL, suffered from unilateral, nonobstructive, infection-free, and previously untreated renal stone (s). Two urinary marker proteins, N-acetyl-beta-gluoosaminidase (NAG) and beta 2-micmglobulin (beta2-M) were monitored in all the patients 1 day before, 1 and 3 day (s) after ESWL using total 100 storage of 3 sessions which is average therapeutical dose. Urinary level or NAG (normal value; 0.29-7.23 U/L) was 1.66+/-1.31 1 day before, 1.97+/-1.57, 2.66+/-2.90 U/L 1 and 3 day (s) after ESWL respectively. beta2-M level (normal value <300 ug/L) was 142+/-137 1 day before. 133+/-100, 151+/-186 ug/L 1 and 3 day(s) alter ESWL, respectively. Consequently it was concluded that ESWL using average therapeutical dose (100 storage) via EDAP LT-01+ litholriptor can hardly develop renal tubular damage.