Korean J Urol.
1990 Dec;31(6):863-868.
Comparative Study of Oral Minocycline Treatment and Intraprostatic Fosfomycin Injection on Nonbacterial Prostatitis
- Affiliations
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- 1Department of Urology, College of Medicine, Ckungbuk National University, Cheongju, Korea.
- 2Department of Urology, Seoul Eulji General Hospital, Seoul, Korea.
Abstract
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The results of intraprostatic injection of fosfomycin were compared to those of oral minocycline therapy in patients with nonbacterial prostatitis. Nonbacterial prostatitis did not recur in 26 out of 33 patients with fosfomycin injected into the prostate and in 16 out of 48 patients treated with oral minocycline. Non-recurrence rate within each group was compared as 78.8 per cent to 33.3 per cent, respectively, demonstrating that intraprostatic fosfomycin treatment was more successful than oral minocycline therapy. The pain and discomfort experienced by the patients during direct injection into the prostate was minimal. Hematuria was always practically present after the injection. Intraprostatic fosfomycin injection is believed to be new alternative method in the treatment of nonbacterial prostatitis.