Korean J Urol.  1987 Feb;28(1):74-78.

M-VAC Combination Chemotherapy in Advanced Bladder Cancer

Affiliations
  • 1Keimyung University, School of Medicine, Taegu, Korea.

Abstract

Patients with advanced carcinoma of the bladder that relapses or persists after conventional therapy have a poor prognosis. The management of the patient with recurrent local or disseminated bladder cancer presents a difficult clinical problem. In l985, Sternberg et al reported 7l% significant tumor regression and 50% complete clinical remission with M-VAC(Methotrexate, Vinblastin, Adriamycin and Cisplatin) combination chemotherapy for treatment of advanced bladder carcinoma Herein, we report 4 cases of M-VAC combination chemotherapy in far advanced bladder carcinoma with had measurable metastatic lesions enough to evaluate the objective response of chemotherapy.

Keyword

bladder cancer; chemotherapy; M-VAC

MeSH Terms

Doxorubicin
Drug Therapy
Drug Therapy, Combination*
Humans
Prognosis
Recurrence
Urinary Bladder Neoplasms*
Urinary Bladder*
Doxorubicin
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