A Clinical Observation on 8 cases with Primary Non-Transitional Cell Carcinoma of Bladder

Kim, Yu Chan; Kim, Kee Soo

Abstract

Eight patients with primary non-transitional cell carcinoma of the bladder during the period from January 1978 to December 1982 were reviewed, and following results ware obtained. 1. Primary non-transitional bladder carcinomas were 8 cases (11%) of 52 bladder carcinomas. 2. The age distribution was from 28 years to 72 years. Male to female ratio was 5 to 3. 3. Hematuria was presented in all cases, dysuria in 2 cases, frequency in 2 cases, lower abdominal pain in 2 cases. 4. Histopathological findings showed squamous cell carcinoma in 3 cases, adenocarcinoma in 3 cases, undifferentiated carcinoma in 1 cases, carcinosarcoma in 1 cases. According to 2Iewett classification, the degree of invasion was stage C in 5 cases, stage B2 in 1 case, stage B1 in 1 case and stage A in 1 case. 5. Five cases arised on lateral wall, 3 cases on dome, 1 case on posterior wall and 1 case on trigone. Four cases were nodular in type. 2 cases were papillary and 2 cases were smooth surface round pedunculated mass. Five cases were single and 3 cases were multiple. 6. 1) In stage C of adenocarcinoma, partial cystectomy was made in 1 case, radical cystectomy with ureteroileocutaneostomy in 1 case, partial cystectomy with postoperative irradiation in 1 case. In former two case, tumor metastasized to periaortic lymphnodes and lumber vertebrae after 6 months post-operatively. 2) Partial cystectomy was performed in 1 case of carcinosarcoma in stage A, tumor recurrence or metastasis did not occur after 1 year post-operatively. 3) In 2 cases of squamous cell carcinoma of stage C, preoperative irradiation with total cystectomy and ureterocutaneostomy was made in 1 case, total cystectomy with ureterocutaneostomy in 1 case and partial cystectomy with 5-FU instillation into the bladder was performed in 1 case of stage B2. In all cases, we couldn't follow up post-operatively. 4) In stage B1 of undifferentiated carcinoma, radical cystectomy with ureteroileocutaneostomy was performed. This case also couldn't be followed up.