Prog Med Phys.  2013 Dec;24(4):243-252. 10.14316/pmp.2013.24.4.243.

Analysis of Acquisition Parameters That Caused Artifacts in Four-dimensional (4D) CT Images of Targets Undergoing Regular Motion

• Sheen H
• Han Y
• Shin E

• KMID: 1910565
• DOI: http://doi.org/10.14316/pmp.2013.24.4.243

Abstract

The aim of this study was to clarify the impacts of acquisition parameters on artifacts in four-dimensional computed tomography (4D CT) images, such as the partial volume effect (PVE), partial projection effect (PPE), and mis-matching of initial motion phases between adjacent beds (MMimph) in cine mode scanning. A thoracic phantom and two cylindrical phantoms (2 cm diameter and heights of 0.5 cm for No.1 and 10 cm for No.2) were scanned using 4D CT. For the thoracic phantom, acquisition was started automatically in the first scan with 5 sec and 8 sec of gantry rotation, thereby allowing a different phase at the initial projection of each bed. In the second scan, the initial projection at each bed was manually synchronized with the inhalation phase to minimize the MMimph. The third scan was intentionally un-synchronized with the inhalation phase. In the cylindrical phantom scan, one bed (2 cm) and three beds (6 cm) were used for 2 and 6 sec motion periods. Measured target volume to true volume ratios (MsTrueV) were computed. The relationships among MMimph, MsTrueV, and velocity were investigated. In the thoracic phantom, shorter gantry rotation provided more precise volume and was highly correlated with velocity when MMimph was minimal. MMimph reduced the correlation. For moving cylinder No. 1, MsTrueV was correlated with velocity, but the larger MMimph for 2 sec of motion removed the correlation. The volume of No. 2 was similar to the static volume due to the small PVE, PPE, and MMimph. Smaller target velocity and faster gantry rotation resulted in a more accurate volume description. The MMimph was the main parameter weakening the correlation between MsTrueV and velocity. Without reducing the MMimph, controlling target velocity and gantry rotation will not guarantee accurate image presentation given current 4D CT technology.

Keyword

4-dimensional computed tomography (4D CT); Partial volume effect (PVE); Partial projection effect (PPE); Mis-matching of initial motion phases between adjacent beds (MMimph)

MeSH Terms

Artifacts*
Four-Dimensional Computed Tomography
Inhalation
Intention

Figure

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  Fig. 1. Cylindrical phantoms and their scan positions.

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  Fig. 2. The method of computing the absolute velocity at each bed.

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  Fig. 3. The correlation between ABS(Vdifference (%)) and the correlation between MsTrueV and velocity in the moving thoracic phantom.

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  Fig. 4. Velocity and MsTrueV values obtained from 1A4P (amplitude 1 cm, period 4 sec), 1A6P, 2A4P, and 2A6P using the thoracic phantom. The scan was automatically started, and the image slice thickness was 2.5 mm.

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  Fig. 5. 4D CT motion artifacts in 1A6P (amplitude 1 cm, period 6 sec) and 2A4P with 0.8 sec gantry rotation time: a) 0% of respiratory phase for 1A6P, b) 30% of respiratory phase for 1A6P, c) 0% of respiratory phase for 2A4P, and d) 30% of respiratory phase for 2A4P.

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  Fig. 6. Calculated velocity vs. percentage phase actually detected by RPM at each bed. The first phase at the X-axis indicates the phase at gantry angle 0. Phantom motion had an amplitude of 0.5 cm and a motion period 4 sec. 1A4P: gantry rotation time 0.8 sec, interleaved between images for 0.4 sec in three beds. In the first bed, the initial phase at a gantry angle of 0 degrees was 40% (actual 41%), while the initial phases changed to 0% and 50% in the second and third beds, respectively. The different initial projection angles of the phantom, which caused large ABS(Vdifference (%)), resulted in different velocities at the same nominal phase percent range among beds, which were 41%, 35%, and 37% in the first, second, and third beds, respectively, for the nominal 40% phase.

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