J Korean Neurosurg Soc.  2001 May;30(5):605-610.

Efficacy of Calcium Sulfate Pellets as Bone Graft Substitute in Lumbar Posterolateral Fusion

Affiliations
  • 1Department of Neurosurgery, School of Medicine, Hanyang University, Seoul, Korea.

Abstract


OBJECTIVE
The authors investigated the efficacy of the calcium sulfate(OsteoSet(r) pellets) as an autograft extender when used to perform posterolateral lumbar fusions.
PATIENTS AND METHODS
Twenty patients who underwent lumbar posterolateral arthrodesis for various spinal diseases between October 1999 and March 2000 were evaluated. Arthrodesis was performed by transpedicular screw fixation and bone grafting with a mixture of autograft + calcium sulfate in a 1:1 ratio. At time intervals of 1, 2, 3, and 6 months, postoperative radiographs were obtained to review the resorption of calcium sulfate and the evidence of fusion. A modified Lenke scale was used to assess the status of the fusion.
RESULTS
At 2 months after operation, the average modified Lenke scale score for the OsteoSet(r) pellets group was 3.8. However at 6 months after operation, the average modified Lenke scale score for the OsteoSet(r) pellets group was 1.8. Resorption of calcium sulfate pellets was revealed in all cases at 6 months after surgery.
CONCLUSION
It is presumed that a combination of calcium sulfate and autograft can play a role as an effective autograft extender in the posterolateral spinal fusion.

Keyword

Calcium sulfate; Lumbar posterolateral fusion; Substitute; Modified Lenke scale

MeSH Terms

Arthrodesis
Autografts
Bone Transplantation
Calcium Sulfate*
Calcium*
Humans
Spinal Diseases
Spinal Fusion
Transplants*
Calcium
Calcium Sulfate
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