J Korean Ophthalmol Soc.  1977 Dec;18(4):391-397.

A Case of Congenital Corneal Staphyloma

• Lee CS
• Lee SH
• Pak BG

Abstract

A case of congenital corneal staphyloma was presented. This 4 year-old boy was premature born and received oxygen in theLincubator during one month after birth. He showed mental retardation, articulation disturbance and gait disturbance. The right eye was free from any anomaly. The left eye was undergone enucleation for cosmetic improvement because of corneal opacity at birth. A detailed histologic examination of the congenital corneal staphyloma was given; epidermidialization of the corneal epithelium, scarring and vascularization of the stroma, with an absence of Bowman's membrane were shown. Descemet-endotheliallayer was completely defective in keratoiridic and corneal-abnormal pigment layer adhesions, but found in the seperated portion between cornea and iris. Iris root was not found in normal position. An abnormal pigment epithelial layer from ciliary epithelium was covered the surface of trabecular meshwork(anterior chamber angle) and an abnormal pigmentation of the trabecular meshwork poorly developed, which was running on iris pigment epithelium and covering inner surface of the cornea. The ciliary body, especially the process was atrophic. The lens was thin membranous and cataractous. Abnormal fibrinous band in the retinal capillary bed was argyrophilic strand. It was suggested that these findings of anterior corneal staphyloma was resulted from primary developmental anomaly of mesodermal and/or neuroectodermal tissue.

MeSH Terms

Bowman Membrane
Capillaries
Cataract
Child, Preschool
Cicatrix
Ciliary Body
Cornea
Corneal Opacity
Epithelium
Epithelium, Corneal
Fibrin
Gait
Humans
Intellectual Disability
Iris
Male
Mesoderm
Neural Plate
Oxygen
Parturition
Pigmentation
Retinaldehyde
Running
Trabecular Meshwork
Fibrin
Oxygen
Retinaldehyde