Korean Circ J.  1995 Apr;25(2):439-450. 10.4070/kcj.1995.25.2.439.

Lipoprotein(a) and Lipoprotein(a) Phenotype in Restenosis after Percutaneous Transluminal Coronary Angioplasty

• Seo DW
• Kim JJ
• Min W
• Song JK
• Park SW
• Park SJ
• Lee JK

• KMID: 1894818
• DOI: http://doi.org/10.4070/kcj.1995.25.2.439

Abstract

BACKGROUND
The purpose of the study was to investigate prospectively the relation of lipoprotein(a)[Lp(a)],apoproteins and serum lipid parameters to restenosis after percutaneous transluminal coronary angioplasyt(PTCA).
METHODS
One hundred and forty-five patients who received successful PTCA were enrolled and their serum levels of lipids, apoproteins and Lp(a) were measured before PTCA. After 6 months of follow-up, the patients were reevaluated for the development of restenosis by coronary angiography, treadmill test or thallium scan.
RESULTS
A total 137 patients could be followed. Restenosis occurred in 71 patients(52%). Clinical parameters(e.g. age, sex, hypertension, diabetes, smoking) and angiographic parameters(e.g. lesion site, type and degree of stenosis) were not significantly different between the group without restenosis and the group with restenosis. Lipid parameters and apoproteins were not associated with restenosis. Lp(a) and Lp(a) phenotype analysis showed no significant difference between the two gruops.
CONCLUSION
Serum lipid parameters, apoproteins and Lp(a) concentration are not associated with restenosis after PTCA and cannot be used as predictios of restenosis.

Keyword

Percutaneous transluminal coronary angioplasty; Lipid parameters; Lipoprotein(a); Lipoprotein(a) phenotype

MeSH Terms

Angioplasty, Balloon, Coronary*
Apoproteins
Coronary Angiography
Exercise Test
Follow-Up Studies
Humans
Hypertension
Lipoprotein(a)*
Phenotype*
Prospective Studies
Thallium
Apoproteins
Lipoprotein(a)
Thallium