Korean J Anesthesiol.  2005 Dec;49(6):810-815. 10.4097/kjae.2005.49.6.810.

The Effect of Right Coronary Artery Stenosis on Right Ventricular Function in Patients Undergoing off Pump Coronary Artery Bypass Surgery

• Shim JK
• Kwak YL
• Oh YJ
• Lee JH
• Choi YR
• Hong YW

• KMID: 1894319
• DOI: http://doi.org/10.4097/kjae.2005.49.6.810

Abstract

BACKGROUND: Right ventricular (RV) function has important prognostic implications in off-pump coronary artery bypass surgery (OPCAB). This study investigated the effect of the extent of right coronary artery (RCA) stenosis on RV function and hemodynamics in patients undergoing OPCAB.
METHODS
Fifty five patients undergoing OPCAB were divided into two groups according to the degree of RCA stenosis; patients with RCA stenosis of < 70% (Group 1, n = 26) and > or = 80% (Group 2, n = 29). RV ejection fraction (RVEF) and RV volumetric parameters were measured using thermodilution technique. Hemodynamic variables were recorded 5 min after induction (T1), 5 min after stabilizer application for anastomosis of the left anterior descending coronary artery (T2), the obtuse marginalis branch (T3) and the RCA (T4) and 5 min after sternum closure (T5).
RESULTS
There were no significant differences in hemodynamic variables between two groups during all study periods except in RVEF. RVEF was significantly greater at T2 and T5 in Group 1 than in Group 2. It decreased significantly at T4 in Group 1 and at T3 and T4 in Group 2 compared to values at T1.
CONCLUSIONS
RVEF significantly decreased at T2 and T5 in group 2 patients. Other variables affecting the RV function such as cardiac output, pulmonary vascular resistance and RV end diastolic volume index showed no differences between the two groups. These findings suggest that the degree of RCA stenosis has contributed to the decrease in RVEF in patients undergoing OPCAB.

Keyword

off-pump coronary artery bypass graft; right coronary artery stenosis; right ventricular function

MeSH Terms

Cardiac Output
Constriction, Pathologic
Coronary Artery Bypass, Off-Pump*
Coronary Stenosis*
Coronary Vessels*
Hemodynamics
Humans
Sternum
Thermodilution
Vascular Resistance
Ventricular Function, Right*