Korean J Otorhinolaryngol-Head Neck Surg.
2007 Nov;50(11):1062-1064.
Rosai-Dorfman Disease in the Neck and Subglottis
- Affiliations
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- 1Department of Otolaryngology-Head and Neck Surgery, Chonnam National University Medical School, Gwangju, Korea. joonkyoo@jnu.ac.kr
Abstract
- Rosai-Dorfman disease is a systemic disease and its etiology is not well understood. It is very rare but established disease. We report a case of Rosai-Dorfman disease occurring in the neck and subglottis. A 18-year-old female had visited with a complaint of bilateral neck mass. Subglottic mass was also detected by flexible laryngoscopy. Lymph node excision and laryngeal microsurgery were performed. The histopathologic findings demonstrated proliferative large histiocytes with clear cytoplasm and rounded nuclei, and lymphagocytosis (emperiopolesis), which were the features of Rosai-Dorfman disease. Rosai-Dorfman disease has various clinical courses. Definitive diagnosis is needed for the appropriate management.
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