Korean J Otolaryngol-Head Neck Surg.  2005 Sep;48(9):1173-1176.

A Case of Invasive Fungal Sinusitis Accompanied with Inflammatory Pseudotumor in Skull Base

Affiliations
  • 1Department of Otorhinolaryngology-Head and Neck Surgery, Ewha Womans University College of Medicine, Seoul, Korea. seungsin2@ewha.ac.kr
  • 2Department of Pathology, Ewha Womans University College of Medicine, Seoul, Korea.

Abstract

Skull base osteomyelitis typically arises as a complication of ear infection in older diabetic patients, but atypical skull base osteomyelitis arising from the sphenoid or occipital bones without external otitis can occur much less frequently and initially may present headache as the only symptom. Inflammatory pseudotumor is an idiopathic condition characterized by the sclerosing inflammation, which mimicks a neoplastic process. Inflammatory pseudotumor involving skull base and cervical spine is distinctly rare and usually indistinguishable from aggressive neoplasms or infection at these area. We report a case which was confirmed histologcally as invasive fungal sinusitis accompanied with inflammatory pseudotumor: the treatment consisted of amphotericin B and systemic steroid therapy but ended in a failure.

Keyword

Skull base; Osteomyelitis; Inflammatory pseudotumor; Invasive fungal sinusitis; Amphotericin

MeSH Terms

Amphotericin B
Ear
Granuloma, Plasma Cell*
Headache
Humans
Inflammation
Occipital Bone
Osteomyelitis
Otitis Externa
Sinusitis*
Skull Base*
Skull*
Spine
Amphotericin B
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