Korean J Lab Med.
2003 Feb;23(1):57-59.
Fatal Acute Hemolytic Transfusion Reaction Due to Anti-E+Fy(a)
- Affiliations
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- 1Department of Laboratory Medicine, Dong-A University College of Medicine, Korea. labmed@damc.or.kr
- 2Department of Laboratory Medicine, Busan Medical Center, Busan, Korea.
- 3Department of Laboratory Medicine, Seoul National University College of Medicine, Seoul, Korea.
Abstract
- A 72-year-old man with a regrowing tongue mass and refractory anemia received two units of compatible red blood cells by saline and albumin phase crossmatching tests. One hour after the last unit, he had a hemolytic transfusion reaction manifested by chest discomfort, fever, redcolored urine, fall in hemoglobin, hemoglobinuria and bilirubinemia. He developed acute renal failure and pulmonary edema and died three days later. Anti-E+Fy(a) antibodies were identified in the patient's serum. This case suggests that indirect antiglobulin crossmatching tests or antibody screening tests are needed for routine pretransfusion tests in Korea.
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