J Korean Surg Soc.  2011 Jul;81(1):70-74. 10.4174/jkss.2011.81.1.70.

Synchronous granular cell tumors in the perianus and chest wall

• Kang DB
• Lee SY
• Jo HJ
• Park WC

• KMID: 1853535
• DOI: http://doi.org/10.4174/jkss.2011.81.1.70

Abstract

Granular cell tumor (GCT) is a rare tumor that originates from the Schwann cells in the skin, soft tissues, and internal organs. Usually, GCTs are clinically benign, although malignant and multifocal forms are very rarely known to occur. Cases of GCT of the perianus are rare, and thus far, no study has reported synchronous GCTs of the perianus and the chest wall. We report a case of a 31-year-old woman with synchronous GCTs of the perianus and the chest wall to have a mind of consideration of the possibility of GCT in the differential diagnosis of perianal tumor.

Keyword

Granular cell tumor; Perianus; Synchronous

MeSH Terms

Adult
Diagnosis, Differential
Female
Granular Cell Tumor
Humans
Schwann Cells
Skin
Thoracic Wall
Thorax

Figure

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  Fig. 1 Histopathological findings of the perianal mass. The lesion was characterized by polygonal cells with abundant eosinophilic granular cytoplasm, and an immunohistochemical study revealed that the cells were positive for the S-100 (A, H&E, ×1; B, H&E, ×40; C, H&E, ×400; D, S-100 protein).

• 

  Fig. 2 Histopathological findings of the chest wall mass. The findings of the chest wall mass were similar to those of the perianal mass; the cells of the perianal mass were also positive for the S-100 protein (A, H&E, ×40; B, H&E, ×400; C, S-100 protein).

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