Korean J Asthma Allergy Clin Immunol.
2006 Jun;26(2):167-171.
A Case of Eosinophilic Gastroenteritis with Elevation of CA-125 Level in Ascites
Abstract
- Eosinophilic gastroenteritis is a rare disease of unknown etiology. It is characterized by massive tissue infiltration of eosinophils in the layer of any area of gastrointestinal tract, increased peripheral blood eosinophil count and various gastrointestinal symptoms. There are mucosal, muscular, and subserosal types, of which the subserosal type may result in the development of eosinophilic ascites. The cancer antigen (CA) 125 tumor associated antigen can be produced by normal cells of different tissues derived from the celomic epithelium. Serum CA-125 serum level can be increased in a diversity of physiological nonmalignant and malignant conditions. We experienced a 23-year-old female patient with eosinophilic gastroenteritis, who was presented with abdominal distention. The patient's serum and ascitic fluid revealed increased CA-125 level. Serum CA-125 level was normalized following the administration of corticosteroids. We report this case with a review of relevant literature.
