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Tuberc Respir Dis.  2009 May;66(5):385-389. 10.4046/trd.2009.66.5.385.

A Case of Congenital Cystic Adenomatoid Malformation of the Lng with Atypical Adenomatous Hyperplasia in Adult

Affiliations
  • 1Department of Internal Medicine, Soonchunhyang University Cheonan Hospital, College of Medicine, Cheonan, Korea. khseo@schca.ac.kr
  • 2Department of Diagnostic Pathology, Soonchunhyang University Cheonan Hospital, College of Medicine, Cheonan, Korea.
  • 3Department of Radiology, Soonchunhyang University Cheonan Hospital, College of Medicine, Cheonan, Korea.

Abstract

Congenital cystic adenomatoid malformation (CCAM), which is classified into five types according to size and bronchial invasion, is a rare type of developmental anomaly of the lung. CCAM is occasionally accompanied by malignancy, such as bronchioloalveolar carcinoma (BAC) or rhabdomyosarcoma. As defined by the WHO, atypical adenomatous hyperplasia (AAH) is a non-invasive spread of atypical epithelial cells in single rows along the alveolar wall, within a lesion that is usually less than 5 mm in diameter. AAH was also regarded as a pre-invasive neoplasia, especially associated with BAC and adenocarcinoma. We report a case of type II CCAM with AAH in adults, with a review of the references.

Keyword

Cystic adenomatoid malformation of lung; Congenital

MeSH Terms

Adenocarcinoma
Adenocarcinoma, Bronchiolo-Alveolar
Adult
Cystic Adenomatoid Malformation of Lung, Congenital
Epithelial Cells
Humans
Hyperplasia
Lung
Rhabdomyosarcoma
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