Korean J Obstet Gynecol.  2012 Jan;55(1):38-42. 10.5468/KJOG.2012.55.1.38.

A case of papillary squamotransitional cell carcinoma in the vagina

• Park BR
• Jeon S
• Bae DH
• Nam GH
• Jeong DJ

• KMID: 1836762
• DOI: http://doi.org/10.5468/KJOG.2012.55.1.38

Abstract

Papillary squamotransitional cell carcinoma (PSTCC) of vagina is not a common disease. Especially primary neoplasm, which is not associated with carcinoma of urinary tract is very rare. To our knowledge, there have been only three reported cases of primary vaginal PSTCC without the history of urothelial carcinoma. Here, we report primary vaginal PSTCC accompanied by cervical squamous carcinoma in situ without the history of urothelial carcinoma with brief review of literature.

Keyword

Papillary squamotransitional cell carcinoma; Vaginal neoplasm

MeSH Terms

Carcinoma, Squamous Cell
Urinary Tract
Vagina
Vaginal Neoplasms

Figure

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  Fig. 1 Colposcopic finding of uterine cervix. Note a mass 2.5 cm in maximal dimension that involved the left posterior fornix (arrow).

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  Fig. 2 (A) Transitional cells with papillary figures are seen (H&E, ×100). (B) Focally keratin forming squamous cell nest is seen (H&E, ×200).

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  Fig. 3 (A) Immunohistochemistry for cytokeratin (CK) 20 is negative (peroxidase, DAB; ×200). (B) Immunohistochemistry for CK 7 is positive in the cytoplasm and cytoplasmic membrane (peroxidase, DAB; ×200).

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  Fig. 4 Magnetic resonance imaging shows ill-defined mass lesion in uterine cervix posterior aspect. Which lesion measured about 2.3 × 2.0 × 1.7 cm (arrow) (A, T2WI sagittal scanning; B, T1WI sagittal scanning; C, T1WI axial scanning).

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  Fig. 5 Magnetic resonance imaging shows no definite mass lesion delineated in uterine cervix (T2WI sagittal scanning).

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